Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

@article{citeulike:1772032, abstract = {Macrophages within the tumor microenvironment facilitate angiogenesis and extracellular-matrix breakdown and remodeling and promote tumor cell motility. Recent studies reveal that direct communication between macrophages and tumor cells leads to invasion and egress of tumor cells into the blood vessels (intravasation). Thus, macrophages are at the center of the invasion microenvironment and are an important drug target for cancer therapy.}, author = {Condeelis, John and Pollard, Jeffrey W. }, citeulike-article-id = {1772032}, doi = {10.1016/j.cell.2006.01.007}, journal = {Cell}, keywords = {macrophages-tumor}, month = {January}, number = {2}, pages = {263--266}, posted-at = {2007-10-16 03:56:51}, priority = {2}, title = {Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis}, url = {http://dx.doi.org/10.1016/j.cell.2006.01.007}, volume = {124}, year = {2006} }

TY - JOUR ID - citeulike:1772032 L3 - citeulike-article-id:1772032 TI - Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis JF - Cell VL - 124 IS - 2 SP - 263 EP - 266 N2 - Macrophages within the tumor microenvironment facilitate angiogenesis and extracellular-matrix breakdown and remodeling and promote tumor cell motility. Recent studies reveal that direct communication between macrophages and tumor cells leads to invasion and egress of tumor cells into the blood vessels (intravasation). Thus, macrophages are at the center of the invasion microenvironment and are an important drug target for cancer therapy. KW - macrophages-tumor AU - Condeelis, John AU - Pollard, Jeffrey PY - 2006/01/27/ UR - http://dx.doi.org/10.1016/j.cell.2006.01.007 ER -