Very low-frequency heart rate variability wave amplitude and sympathetic stimulation-characterization and modeling

@article{citeulike:1129759, abstract = {The purpose of this study was to assess the relationship between very low-frequency heart rate variability (LFHR) wave amplitude and the degree of sympathetic stimulation. We developed a computerized system for the controlled increase of heart rate (HR) by isoproterenol (ISP), with which we obtained a series of stabilized HR levels in conscious freely moving rats. We found that LFHR amplitude rises gradually as a function of the average HR for each level until it reaches a point where additional increases in average HR are associated with gradual decrease in LFHR amplitude. We successfully built and fitted a model of LFHR amplitude to the experimental results. The fact that our model fits the experimental data well may suggest a possible relationship between our LFHR amplitude findings and the basic physiologic properties of the HR-ISP system inherent in our model.}, author = {Leor-Librach, R. J. and Eliash, S. and Kaplinsky, E. and Bobrovsky, B. Z. }, citeulike-article-id = {1129759}, journal = {Biomedical Engineering, IEEE Transactions on}, keywords = {neuropathy}, number = {7}, pages = {797--803}, posted-at = {2007-03-14 18:17:22}, priority = {2}, title = {Very low-frequency heart rate variability wave amplitude and sympathetic stimulation-characterization and modeling}, url = {http://ieeexplore.ieee.org/xpls/abs\_all.jsp?arnumber=1206488}, volume = {50}, year = {2003} }

TY - JOUR ID - citeulike:1129759 L3 - citeulike-article-id:1129759 TI - Very low-frequency heart rate variability wave amplitude and sympathetic stimulation-characterization and modeling JF - Biomedical Engineering, IEEE Transactions on VL - 50 IS - 7 SP - 797 EP - 803 N2 - The purpose of this study was to assess the relationship between very low-frequency heart rate variability (LFHR) wave amplitude and the degree of sympathetic stimulation. We developed a computerized system for the controlled increase of heart rate (HR) by isoproterenol (ISP), with which we obtained a series of stabilized HR levels in conscious freely moving rats. We found that LFHR amplitude rises gradually as a function of the average HR for each level until it reaches a point where additional increases in average HR are associated with gradual decrease in LFHR amplitude. We successfully built and fitted a model of LFHR amplitude to the experimental results. The fact that our model fits the experimental data well may suggest a possible relationship between our LFHR amplitude findings and the basic physiologic properties of the HR-ISP system inherent in our model. KW - neuropathy AU - Leor-Librach, RJ AU - Eliash, S AU - Kaplinsky, E AU - Bobrovsky, BZ PY - 2003/// UR - http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=1206488 ER -