Mitochondrial DNA and the origins of the domestic horse.

@article{citeulike:1916461, abstract = {The place and date of the domestication of the horse has long been a matter for debate among archaeologists. To determine whether horses were domesticated from one or several ancestral horse populations, we sequenced the mitochondrial D-loop for 318 horses from 25 oriental and European breeds, including American mustangs. Adding these sequences to previously published data, the total comes to 652, the largest currently available database. From these sequences, a phylogenetic network was constructed that showed that most of the 93 different mitochondrial (mt)DNA types grouped into 17 distinct phylogenetic clusters. Several of the clusters correspond to breeds and/or geographic areas, notably cluster A2, which is specific to Przewalski's horses, cluster C1, which is distinctive for northern European ponies, and cluster D1, which is well represented in Iberian and northwest African breeds. A consideration of the horse mtDNA mutation rate together with the archaeological timeframe for domestication requires at least 77 successfully breeding mares recruited from the wild. The extensive genetic diversity of these 77 ancestral mares leads us to conclude that several distinct horse populations were involved in the domestication of the horse.}, address = {Biopsytec Analytik GmbH, Marie-Curie-Strasse 1, 53359 Rheinbach, Germany. jansen@biopsytec.com}, author = {Jansen, T. and Forster, P. and Levine, M. A. and Oelke, H. and Hurles, M. and Renfrew, C. and Weber, J. and Olek, K. }, citeulike-article-id = {1916461}, doi = {http://dx.doi.org/10.1073/pnas.152330099}, issn = {0027-8424}, journal = {Proc Natl Acad Sci U S A}, keywords = {cultural-evolution, evo-domestication, evolution, evolutionary-genomics}, month = {August}, number = {16}, pages = {10905--10910}, posted-at = {2008-01-14 20:51:54}, priority = {3}, title = {Mitochondrial DNA and the origins of the domestic horse.}, url = {http://dx.doi.org/10.1073/pnas.152330099}, volume = {99}, year = {2002} }

TY - JOUR ID - citeulike:1916461 L3 - citeulike-article-id:1916461 TI - Mitochondrial DNA and the origins of the domestic horse. JF - Proc Natl Acad Sci U S A VL - 99 IS - 16 SP - 10905 EP - 10910 AD - Biopsytec Analytik GmbH, Marie-Curie-Strasse 1, 53359 Rheinbach, Germany. jansen@biopsytec.com SN - 0027-8424 N2 - The place and date of the domestication of the horse has long been a matter for debate among archaeologists. To determine whether horses were domesticated from one or several ancestral horse populations, we sequenced the mitochondrial D-loop for 318 horses from 25 oriental and European breeds, including American mustangs. Adding these sequences to previously published data, the total comes to 652, the largest currently available database. From these sequences, a phylogenetic network was constructed that showed that most of the 93 different mitochondrial (mt)DNA types grouped into 17 distinct phylogenetic clusters. Several of the clusters correspond to breeds and/or geographic areas, notably cluster A2, which is specific to Przewalski's horses, cluster C1, which is distinctive for northern European ponies, and cluster D1, which is well represented in Iberian and northwest African breeds. A consideration of the horse mtDNA mutation rate together with the archaeological timeframe for domestication requires at least 77 successfully breeding mares recruited from the wild. The extensive genetic diversity of these 77 ancestral mares leads us to conclude that several distinct horse populations were involved in the domestication of the horse. KW - cultural-evolution KW - evo-domestication KW - evolution KW - evolutionary-genomics AU - Jansen, T AU - Forster, P AU - Levine, MA AU - Oelke, H AU - Hurles, M AU - Renfrew, C AU - Weber, J AU - Olek, K PY - 2002/08/06/ UR - http://dx.doi.org/10.1073/pnas.152330099 ER -