Phenome connections

by: Martin Oti, Martijn A Huynen, Han G Brunner

Trends in Genetics, Vol. 24, No. 3. (March 2008), pp. 103-106.

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Abstract

Human phenomics is about to come of age with studies that systematically assess the overlap and relationships among all human genetic diseases. A recent study by Andrey Rzhetsky and colleagues illustrates the power of phenomics by revealing links between conditions that were thought to be distinct, suggesting that they share a genetic basis. Their results imply that the human phenome can be viewed as a landscape of interrelated diseases, reflecting overlapping molecular causation.

@article{citeulike:2461016, abstract = {Human phenomics is about to come of age with studies that systematically assess the overlap and relationships among all human genetic diseases. A recent study by Andrey Rzhetsky and colleagues illustrates the power of phenomics by revealing links between conditions that were thought to be distinct, suggesting that they share a genetic basis. Their results imply that the human phenome can be viewed as a landscape of interrelated diseases, reflecting overlapping molecular causation.}, author = {Oti, Martin and Huynen, Martijn A. and Brunner, Han G. }, citeulike-article-id = {2461016}, doi = {10.1016/j.tig.2007.12.005}, journal = {Trends in Genetics}, keywords = {diseaseomics, genotype-to-phenotype, informatics, reviews}, month = {March}, number = {3}, pages = {103--106}, posted-at = {2008-05-06 16:57:20}, priority = {3}, title = {Phenome connections}, url = {http://dx.doi.org/10.1016/j.tig.2007.12.005}, volume = {24}, year = {2008} }

RIS record

TY - JOUR ID - citeulike:2461016 L3 - citeulike-article-id:2461016 TI - Phenome connections JF - Trends in Genetics VL - 24 IS - 3 SP - 103 EP - 106 N2 - Human phenomics is about to come of age with studies that systematically assess the overlap and relationships among all human genetic diseases. A recent study by Andrey Rzhetsky and colleagues illustrates the power of phenomics by revealing links between conditions that were thought to be distinct, suggesting that they share a genetic basis. Their results imply that the human phenome can be viewed as a landscape of interrelated diseases, reflecting overlapping molecular causation. KW - diseaseomics KW - genotype-to-phenotype KW - informatics KW - reviews AU - Oti, Martin AU - Huynen, Martijn AU - Brunner, Han PY - 2008/03// UR - http://dx.doi.org/10.1016/j.tig.2007.12.005 ER -

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