Group G streptococcal bacteraemia: an opportunistic infection associated with immune senescence.

@article{citeulike:564365, abstract = {The number of cases of group G streptococcal bacteraemia reported worldwide is increasing. Twenty-six cases of group G streptococcal bacteraemia were identified during a 70-month period at a single university teaching hospital in Sheffield, UK. These cases represented 20\% of all bacteraemias due to beta-hemolytic Streptococci, a higher proportion than previously reported. The median age of these cases was 72 y and although medical comorbidities were common only cutaneous ulceration was clearly linked to the presenting syndromes. The skin was the source of infection in 16 cases (62\%) and the most frequent clinical presentations were cellulitis in 13 cases (50\%) and endovascular infection in 5 (19\%). Eight (31\%) of the cases died during the period of follow-up but only 2 deaths were related to the streptococcal infection. Immunosenescence represents the major risk factor for group G streptococcal infection in this population and comorbidities, including carcinoma, may be markers of the senescent immune system rather than direct contributing factors to group G streptococcal bacteraemia.}, address = {Department of Infectious Diseases, Royal Hallamshire Hospital, Sheffield, UK.}, author = {Lewthwaite, P. and Parsons, H. K. and Bates, C. J. and McKendrick, M. W. and Dockrell, D. H. }, citeulike-article-id = {564365}, issn = {0036-5548}, journal = {Scand J Infect Dis}, keywords = {bacteremia, ggs}, number = {2}, pages = {83--87}, posted-at = {2006-03-27 08:32:09}, priority = {2}, title = {Group G streptococcal bacteraemia: an opportunistic infection associated with immune senescence.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/11928858}, volume = {34}, year = {2002} }

TY - JOUR ID - citeulike:564365 L3 - citeulike-article-id:564365 TI - Group G streptococcal bacteraemia: an opportunistic infection associated with immune senescence. JF - Scand J Infect Dis VL - 34 IS - 2 SP - 83 EP - 87 AD - Department of Infectious Diseases, Royal Hallamshire Hospital, Sheffield, UK. SN - 0036-5548 N2 - The number of cases of group G streptococcal bacteraemia reported worldwide is increasing. Twenty-six cases of group G streptococcal bacteraemia were identified during a 70-month period at a single university teaching hospital in Sheffield, UK. These cases represented 20% of all bacteraemias due to beta-hemolytic Streptococci, a higher proportion than previously reported. The median age of these cases was 72 y and although medical comorbidities were common only cutaneous ulceration was clearly linked to the presenting syndromes. The skin was the source of infection in 16 cases (62%) and the most frequent clinical presentations were cellulitis in 13 cases (50%) and endovascular infection in 5 (19%). Eight (31%) of the cases died during the period of follow-up but only 2 deaths were related to the streptococcal infection. Immunosenescence represents the major risk factor for group G streptococcal infection in this population and comorbidities, including carcinoma, may be markers of the senescent immune system rather than direct contributing factors to group G streptococcal bacteraemia. KW - bacteremia KW - ggs AU - Lewthwaite, P AU - Parsons, HK AU - Bates, CJ AU - McKendrick, MW AU - Dockrell, DH PY - 2002/// UR - http://view.ncbi.nlm.nih.gov/pubmed/11928858 ER -