Extending in vitro conditioning in Aplysia to analyze operant and classical processes in the same preparation.

@article{citeulike:877187, abstract = {Operant and classical conditioning are major processes shaping behavioral responses in all animals. Although the understanding of the mechanisms of classical conditioning has expanded significantly, the understanding of the mechanisms of operant conditioning is more limited. Recent developments in Aplysia are helping to narrow the gap in the level of understanding between operant and classical conditioning, and have raised the possibility of studying the neuronal processes underlying the interaction of operant and classical components in a relatively complex learning task. In the present study, we describe a first step toward realizing this goal, by developing a single in vitro preparation in which both operant and classical conditioning can be studied concurrently. The new paradigm reproduced previously published results, even under more conservative and homogenous selection criteria and tonic stimulation regime. Moreover, the observed learning was resistant to delay, shortening, and signaling of reinforcement.}, address = {Department of Neurobiology and Anatomy, W.M. Keck Center for the Neurobiology of Learning and Memory, The University of Texas Medical School at Houston, Houston, Texas 77030, USA. bjoern@brembs.net}, author = {Brembs, B. and Baxter, D. A. and Byrne, J. H. }, citeulike-article-id = {877187}, doi = {http://dx.doi.org/10.1101/lm.74404}, issn = {1072-0502}, journal = {Learn Mem}, keywords = {aplysia, conditioning, learning, memory, neurobiology, neuroscience, operant, physiology, slug, snail}, number = {4}, pages = {412--420}, posted-at = {2006-09-29 08:01:36}, priority = {0}, title = {Extending in vitro conditioning in Aplysia to analyze operant and classical processes in the same preparation.}, url = {http://dx.doi.org/10.1101/lm.74404}, volume = {11}, year = {2004} }

TY - JOUR ID - citeulike:877187 L3 - citeulike-article-id:877187 TI - Extending in vitro conditioning in Aplysia to analyze operant and classical processes in the same preparation. JF - Learn Mem VL - 11 IS - 4 SP - 412 EP - 420 AD - Department of Neurobiology and Anatomy, W.M. Keck Center for the Neurobiology of Learning and Memory, The University of Texas Medical School at Houston, Houston, Texas 77030, USA. bjoern@brembs.net SN - 1072-0502 N2 - Operant and classical conditioning are major processes shaping behavioral responses in all animals. Although the understanding of the mechanisms of classical conditioning has expanded significantly, the understanding of the mechanisms of operant conditioning is more limited. Recent developments in Aplysia are helping to narrow the gap in the level of understanding between operant and classical conditioning, and have raised the possibility of studying the neuronal processes underlying the interaction of operant and classical components in a relatively complex learning task. In the present study, we describe a first step toward realizing this goal, by developing a single in vitro preparation in which both operant and classical conditioning can be studied concurrently. The new paradigm reproduced previously published results, even under more conservative and homogenous selection criteria and tonic stimulation regime. Moreover, the observed learning was resistant to delay, shortening, and signaling of reinforcement. KW - aplysia KW - conditioning KW - learning KW - memory KW - neurobiology KW - neuroscience KW - operant KW - physiology KW - slug KW - snail AU - Brembs, B AU - Baxter, DA AU - Byrne, JH PY - 2004///g UR - http://dx.doi.org/10.1101/lm.74404 ER -