Genetically manipulated mice: a powerful tool with unsuspected caveats

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1 1dge 2dge aa aborigine abp abpp acarbose ace ace2 acei aceiarb acetylation acid-base acidosis activity activity-based acute adam adductome adenoine adenosine adh adipokine adiponectin adma adpkd adrenal adrenomedullin affinity affy aft ag age ager1 agilent aging agreement ai aii akt album albumin alcohol aldh aldh2 aldosterone alignment alkp allergy allhat alpk1 ampk amplification analgesics ancova androgen anemia aneurysm angiogenesis anima animal ann annexin anoikis anorexia anova anp ans antacid anthropometry antibiotics antibody antiplatelet antisense ap1 apc apelin aplicing apoe apoptosis appetite aptamer aqp aquaporin ar arb ards arecoline arf arkadia arsenic arthritis ase asia aspirin assocaition assocation association assumption asymptote at1 at2 atm atp attirtion attrition autoantibody autoimminity autoimmunity automation autophagy avf b2m bac bacteria baculovirus bagging bayes bcaa bead berberine beta-adrenergic betablocker beta-blocker betel bia bias bifc biobank biofilm bioinformatics bioinformatis biomaker biomarker biopsy biosensor blast bleeding blog blood bma bmi bmp bmp7 bnp bone boosting bootstrap boratory bounded bp bret bun bv c ca cachexia cachexmia cad cadium cadmium cage calcification calcimimetics calcium calmodulin calorimetry calpain calreticulin camp cancer candiate-gene candidate-gene canitine cannabinoid capd cardiomegaly carnitine carnosinase cart cartotenoid case-cohort case-control caspase cat catabolism catalase catenin catheter causality causation caveolin ccb ccl2 ccn ccr cd cd1 cd44 ce cea cell cell-adhesion cell-array cell-based cell-culture cell-cycle cell-line cell-microarray censor ceramide cgh cgmp change changepoiint changepoint change-point chaqngepoint chd chemical-genetics chemogenomics chemoinformatics chemokine chemotherapy chf china chinese chip chip-chip chip-cloning chip-snp chk cho choline cholinergic chromatin chromatography chymase ciliopathy cin ck2 ckd class-effect classification clathrin cloning cluster clustering cml cmv cnv co cobalt coffee cohort colagen colchicine collage collagen collinearity colon comet comet-assay communication comorbidity company compeitive-pcr competing-risk competitive-pcr competivie-pcr complement complex compliance concentration conditional confidence-interval confounding connexin control copper copula core-curriculum cortisol cotinine cox cox2 cpc cqi cr creatinine creb cre-lox critical-care crossover cross-over cross-platform cross-species crp crrt cryopyrin csa ct ctg ctgf curcumin cure cusum cv cxcr2 cyclin cyp450 cyst cystatin cytokine cytokine-receptor cytoscape cytoskeleton cytotoxicity database data-mining dataset dbdb dc decision-analysis decorin decoy defensin degradation delirium delivery dendritic-cell dentistry depression design dhea dhplc diagnosis dialysate dialysis dialyzer diastolic dichotomization diet dige dipstick dipyridamole disease disease-management disparity distribution diuretics diurnal dm dn dna-adduct dna-da dna-damage dna-ddamage dna-pk dna-synthesis doca-salt domain dopamine dopps dose-reponse dose-response dpi drug drug-discovery dt dvt dyanamic-range dye-swap dynamic-range e2f ebm ebv ecm ecoli ecology edema education effect-size effusion egf egfr egr1 eia eicosanoid electrolyte electroporation electroporatrion electroportaion elisa embryology emodin emsa emt enamia encode enddysf endothelial-dysfunction endothelila-dysfunction endothelium endotoxin endpoint end-point energy enos enoxacin ent environment enzyme epidemiology epigenetics epiregulin epistasis epithelium epo eqtl erk erm error er-stress esirna est estrogen et et1 ethics ets excel exercise extraction fak family far-western fasting fat fb fbat fc fdr fetal fetuin ffpe ffq fgf fhs fibrinogen fibroblast fibrocyte fibromyalgia fibronectin fibrosis fish fish-oil flow-cytometry fluid fluorescence fly forest formaldehyde foxo fracpoly fractal fracture frailty fret fructose ft-ms fto function functional-regression function-regression futility fuzzy fxr gaba galectin gam gap gas gata gauss gb gc gc-ms ge gee gelatin gencer gender gene gene-environment gene-gene gene-synthesis gene-targeting gene-therapy genetics genome genomics geography gerd geriatric geriatrics gfr gh ghrelin gi glcnac gllamm glm glucose glut glutamine glycation glycemia glycemic-control glycmoics glycomics glyoxalase gn gnetics gof good gout gpcr graph graphics gremlin grid grk grn gsh gsk gsk3 gst guideline guidline gwa gyn gynecomastia haplotype hapmap has hba1c hbv hcc hcv hcy hd hdac hdf hdl he heart-rate hedgehog hek293 helicase hematuria hemoglobin heparin hepatocyte hepatotyte herb heritability hexosamine hf hfe hg hgf hgp hif hif1 hif2 high-fat hirsutism histidine histone hiv hk2 hla hmgb hnf ho ho1 hormone hospital hospital-based hospitalization housekeeping hp hplc hprt hrs hsc hsp hsp27 hsp70 hsp90 ht hts huge human huvec hvj hwe hyaluronan hydrodynamic hyperfiltration hyperglycemia hyperlipidemia hyperosmolality hypertension hypertfiltration hypertonicity hypertrophy hypotension hypoxia icam icam1 icp-ms icu id identifier idn idw ie ief ifg1 ifn igan igf igf1 igg igm ih ihc ihg il il1 il6 ilk illumina image imaging imcd immortal-time-bias immunity immunoblot immuno-pcr impuputation imputaion imputation indel inducible infection inflammasome inflammasone inflammation inflammtion influenza informative-censor inhibitor innate insulin insulin-receptor integrin interaction interactome intersection interval-censor intrumental-variable inverse-sampling ipcw ir iron irs ish isoform isotype itraq iv jak japan java jnk joint-model jun k kallikrein kallistatin kap keep kidney kidney-specific kim1 kinase kinin kinome kinomics klf klf5 kloho klotho knockout korea label-free laboratory lactase lasso latent latent-class latent-growth latent-tgfb lbp lc lc-ms lcr ldl lead left-censor left-censoring leptin lft lic licorice lifestyle limma lims linux liongitudinal lipid lipidomics lipid-signaling liver liver-regeneration liver-regneration llcpk1 llc-pk1 lna location lod logic logic-regression log-linear log-normal longitudinal low-density lox lpd lpo lps lr lt ltq-ms luminex lung lvh lysozyme m macrophage management mao mapk markov mars mashup mast-cell matching matlab mc mcp mcp1 mdck mdr mdrd mds measurement-bias measurement-error meat mechanical-stress mediation megalin megsin melamine melanocortin melting-curve membran membrane membrane-protein mendelian menin menopaus mercury mes13 mes3 mesangial met meta-analysis meta-anaysis meta-anlysis metabolism metabolomics metabonomics metacid metagenomics metal metformin method methylation mg mgo mia mice microanalysis microaray microarrapy microarray microarrayer microbiome microfludics microfluidics micronucleus microscope midkine milk mineral minipump mirna missing mitochondria mitogenesis mixed-effect mixed-effects mixed-model mixed-modl mixture mk2 mkicroarray mmf mmp mn model model-averaging model-organism model-selection molecular-beacon monotonic morality mortality mouse mrfit mri mrm mrp mrsa ms msh msm msp msu mthfr mthylation mtor multinomial multiplex multiplicicy multiplicity multivariate muscarinic mutagenesis mv myc myd88 myoglobin myosin n na nac nad nahsit nail name nash ncs necrosis nephrectomy nephrin nephrotoxicity nerve nested network netwrok neuro neurology nfat nfkb nflammation ngal nhanes nhi niacin nicotinic nitration nitrosamine nlr nmf nmr nnt no nondn nonlinear nonparametric nonviral normality normalization notch nox nrk49f nrk-49f nrk52e ntuh nuclear-medicine nuclear-receptor nucleocytoplasmic nucleoside nucleus nutrigenomics nutrition nutrtion oat obesity obessity occupation oct odc off-target ogg oha omics oncogene ontology ordinal osp osteopontin osteoporosis ou outcome outlier oxicology p p16 p21 p27 p2x p300 p38 p53 pad padlock pai1 pain palliative parp pathogenesis pathology pathway pbat pbl pbmc pca pcr pd pde