Serum anti-Mullerian hormone is more strongly related to ovarian follicular status than serum inhibin B, estradiol, FSH and LH on day 3

@article{citeulike:2327060, abstract = {BACKGROUND: The study aim was to compare the relationship between serum anti-Mullerian hormone (AMH) levels and other markers of ovarian function with early antral follicle count on day 3. METHODS: A total of 75 infertile women was studied prospectively. On cycle day 3, serum levels of AMH, inhibin B, estradiol (E2), FSH and LH levels were measured, and the number of early antral follicles (2-10 mm in diameter) estimated at ultrasound scanning to compare the strengths of hormonal-follicular correlations. RESULTS: Median (range) serum levels of AMH, inhibin B, E2, FSH and LH were 1.39 ng/ml (0.24-6.40), 90 (16-182) pg/ml, 31 (15-111) pg/ml, 7.0 (2.9-19.3) mIU/ml and 4.7 (1.2-11.7) mIU/ml respectively, and follicular count was 12 (1-35). Serum AMH levels were more strongly correlated (P < 0.001) with follicular count (r = 0.74, P < 0.0001) than were serum levels of inhibin B (r = 0.29, P < 0.001), E2 (r = -0.08, P = NS), FSH (r = -0.29, P < 0.001) and LH (r = 0.05, P = NS). CONCLUSIONS: Serum AMH levels were more robustly correlated with the number of early antral follicles than inhibin B, E2, FSH and LH on cycle day 3. This suggests that AMH may reflect ovarian follicular status better than the usual hormone markers. 10.1093/humrep/deg042}, author = {Fanchin, Renato and Schonauer, Luca M. and Righini, Claudia and Guibourdenche, Jean and Frydman, Rene and Taieb, Joelle }, citeulike-article-id = {2327060}, doi = {10.1093/humrep/deg042}, journal = {Hum. Reprod.}, keywords = {anti-mullerian, estradiol, fsh, lh}, month = {February}, number = {2}, pages = {323--327}, posted-at = {2008-02-03 19:51:10}, priority = {2}, title = {Serum anti-Mullerian hormone is more strongly related to ovarian follicular status than serum inhibin B, estradiol, FSH and LH on day 3}, url = {http://dx.doi.org/10.1093/humrep/deg042}, volume = {18}, year = {2003} }

TY - JOUR ID - citeulike:2327060 L3 - citeulike-article-id:2327060 TI - Serum anti-Mullerian hormone is more strongly related to ovarian follicular status than serum inhibin B, estradiol, FSH and LH on day 3 JF - Hum. Reprod. VL - 18 IS - 2 SP - 323 EP - 327 N2 - BACKGROUND: The study aim was to compare the relationship between serum anti-Mullerian hormone (AMH) levels and other markers of ovarian function with early antral follicle count on day 3. METHODS: A total of 75 infertile women was studied prospectively. On cycle day 3, serum levels of AMH, inhibin B, estradiol (E2), FSH and LH levels were measured, and the number of early antral follicles (2-10 mm in diameter) estimated at ultrasound scanning to compare the strengths of hormonal-follicular correlations. RESULTS: Median (range) serum levels of AMH, inhibin B, E2, FSH and LH were 1.39 ng/ml (0.24-6.40), 90 (16-182) pg/ml, 31 (15-111) pg/ml, 7.0 (2.9-19.3) mIU/ml and 4.7 (1.2-11.7) mIU/ml respectively, and follicular count was 12 (1-35). Serum AMH levels were more strongly correlated (P < 0.001) with follicular count (r = 0.74, P < 0.0001) than were serum levels of inhibin B (r = 0.29, P < 0.001), E2 (r = -0.08, P = NS), FSH (r = -0.29, P < 0.001) and LH (r = 0.05, P = NS). CONCLUSIONS: Serum AMH levels were more robustly correlated with the number of early antral follicles than inhibin B, E2, FSH and LH on cycle day 3. This suggests that AMH may reflect ovarian follicular status better than the usual hormone markers. 10.1093/humrep/deg042 KW - anti-mullerian KW - estradiol KW - fsh KW - lh AU - Fanchin, Renato AU - Schonauer, Luca AU - Righini, Claudia AU - Guibourdenche, Jean AU - Frydman, Rene AU - Taieb, Joelle PY - 2003/02/01/ UR - http://dx.doi.org/10.1093/humrep/deg042 ER -