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The Hofmeister effect as seen by SAXS in protein solutions

Current Opinion in Colloid & Interface Science, Vol. 9, No. 1-2. (August 2004), pp. 112-116.


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Protein interactions in solution are conveniently analysed with small angle X-ray scattering (SAXS). Such an analysis has shown that the addition of monovalent salt induces an additional attraction between macromolecules. A differential effect of the anions is observed, which follows the order of the Hofmeister series. Such experimental observations should be helpful to test the adequacy of theoretical models.


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