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ndoelkers chemokine [25 articles]

Artikler nylig sendt til ndoelkers bibliotek klassifisert med nøkkelordet chemokine. You can also see everyone's chemokine.
  • Characterization of the role of the N-loop of MIP-1 beta in CCR5 binding.
    Biochemistry, Vol. 41, No. 46. (19 November 2002), pp. 13548-13555.
    by A Bondue, SC Jao, C Blanpain, M Parmentier, PJ LiWang
    posted to chemokine ccr5 binding by ndoelker on 2007-01-20 15:08:17 as *** along with 1 group LabCompMed
  • A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity.
    Proc Natl Acad Sci U S A, Vol. 96, No. 10. (May 1999), pp. 5698-703.
    by M Baba, O Nishimura, N Kanzaki, M Okamoto, H Sawada, Y Iizawa, M Shiraishi, Y Aramaki, K Okonogi, Y Ogawa, K Meguro, M Fujino
    posted to antagonist bibtex-nicole ccr5 chemokine gpcr by ndoelker on 2006-10-30 16:53:04 as read along with 1 group LabCompMed
  • The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle.
    J Biol Chem, Vol. 278, No. 7. (Feb 2003), pp. 5179-87.
    by Cã©dric Blanpain, Benjamin J Doranz, Antoine Bondue, Cã©dric Govaerts, Anne De Leener, Gilbert Vassart, Robert W Doms, Amanda Proudfoot, Marc Parmentier
    posted to bibtex-nicole binding ccr5 chemokine gpcr by ndoelker on 2006-10-30 16:53:03 as read along with 1 group LabCompMed
  • Identification of residues of CXCR4 critical for human immunodeficiency virus coreceptor and chemokine receptor activities.
    J Biol Chem, Vol. 275, No. 31. (Aug 2000), pp. 23736-44.
    by A Brelot, N Heveker, M Montes, M Alizon
    posted to bibtex-nicole binding chemokine cxcr4 gpcr by ndoelker on 2006-10-30 16:53:03 as read along with 1 group LabCompMed
  • Mutagenesis of CXCR4 identifies important domains for human immunodeficiency virus type 1 X4 isolate envelope-mediated membrane fusion and virus entry and reveals cryptic coreceptor activity for R5 isolates.
    J Virol, Vol. 73, No. 8. (Aug 1999), pp. 6598-609.
    by DJ Chabot, PF Zhang, GV Quinnan, CC Broder
    posted to bibtex-nicole chemokine cxcr4 gpcr by ndoelker on 2006-10-30 16:53:03 as read along with 1 group LabCompMed
  • Generation of predictive pharmacophore models for CCR5 antagonists: study with piperidine- and piperazine-based compounds as a new class of HIV-1 entry inhibitors.
    J Med Chem, Vol. 46, No. 21. (Oct 2003), pp. 4501-15.
    by Asim K Debnath
    posted to antagonist bibtex-nicole ccr5 chemokine gpcr pharmacophore by ndoelker on 2006-10-30 16:53:03 as read along with 1 group LabCompMed
  • A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5.
    Proc Natl Acad Sci U S A, Vol. 97, No. 10. (May 2000), pp. 5639-44.
    by T Dragic, A Trkola, DA Thompson, EG Cormier, FA Kajumo, E Maxwell, SW Lin, W Ying, SO Smith, TP Sakmar, JP Moore
    posted to bibtex-nicole binding ccr5 chemokine gpcr mutation by ndoelker on 2006-10-30 16:53:03 as read along with 1 group LabCompMed
  • Molecular interactions of cyclam and bicyclam non-peptide antagonists with the CXCR4 chemokine receptor.
    J Biol Chem, Vol. 276, No. 17. (Apr 2001), pp. 14153-60.
    by LO Gerlach, RT Skerlj, GJ Bridger, TW Schwartz
    posted to antagonist bibtex-nicole chemokine cxcr4 gpcr by ndoelker on 2006-10-30 16:53:02 as read along with 1 group LabCompMed
  • Metal ion enhanced binding of AMD3100 to Asp262 in the CXCR4 receptor.
    Biochemistry, Vol. 42, No. 3. (Jan 2003), pp. 710-7.
    by Lars O Gerlach, Janus S Jakobsen, Kasper P Jensen, Mette R Rosenkilde, Renato T Skerlj, Ulf Ryde, Gary J Bridger, Thue W Schwartz
    posted to bibtex-nicole binding chemokine cxcr4 gpcr by ndoelker on 2006-10-30 16:53:02 as read along with 1 group LabCompMed
  • The TXP motif in the second transmembrane helix of CCR5. A structural determinant of chemokine-induced activation.
    J Biol Chem, Vol. 276, No. 16. (Apr 2001), pp. 13217-13225.
    by C Govaerts, C Blanpain, X Deupi, S Ballet, JA Ballesteros, SJ Wodak, G Vassart, L Pardo, M Parmentier
    posted to activation bibtex-nicole ccr5 chemokine gpcr helix transmembrane txp by ndoelker on 2006-10-30 16:53:02 as read along with 1 group LabCompMed
  • Activation of CCR5 by chemokines involves an aromatic cluster between transmembrane helices 2 and 3.
    J Biol Chem, Vol. 278, No. 3. (Jan 2003), pp. 1892-903.
    by Cã©dric Govaerts, Antoine Bondue, Jean Y Springael, Mireia Olivella, Xavier Deupi, Emmanuel Le Poul, Shoshana J Wodak, Marc Parmentier, Leonardo Pardo, Cã©dric Blanpain
    posted to activation aromatic bibtex-nicole ccr5 chemokine cluster gpcr tm2 tm3 by ndoelker on 2006-10-30 16:53:02 as read along with 1 group LabCompMed
  • Mutation of Asp(171) and Asp(262) of the chemokine receptor CXCR4 impairs its coreceptor function for human immunodeficiency virus-1 entry and abrogates the antagonistic activity of AMD3100.
    Mol Pharmacol, Vol. 60, No. 1. (Jul 2001), pp. 164-73.
    by S Hatse, K Princen, LO Gerlach, G Bridger, G Henson, E De Clercq, TW Schwartz, D Schols
    posted to bibtex-nicole binding chemokine cxcr4 gpcr mutation by ndoelker on 2006-10-30 16:53:02 as read along with 1 group LabCompMed
  • Identification of gp120 binding sites on CXCR4 by using CD4-independent human immunodeficiency virus type 2 Env proteins.
    J Virol, Vol. 77, No. 2. (Jan 2003), pp. 931-42.
    by George Lin, Frã©dã©ric Baribaud, Josephine Romano, Robert W Doms, James A Hoxie
    posted to bibtex-nicole binding chemokine cxcr4 gpcr by ndoelker on 2006-10-30 16:53:00 as read along with 1 group LabCompMed
  • Five-transmembrane domains appear sufficient for a G protein-coupled receptor: functional five-transmembrane domain chemokine receptors.
    Proc Natl Acad Sci U S A, Vol. 96, No. 14. (Jul 1999), pp. 7922-7927.
    by K Ling, P Wang, J Zhao, YL Wu, ZJ Cheng, GX Wu, W Hu, L Ma, G Pei
    posted to bibtex-nicole ccr5 chemokine cxcr4 gpcr transmembrane by ndoelker on 2006-10-30 16:53:00 as read along with 1 group LabCompMed
  • Novel low molecular weight spirodiketopiperazine derivatives potently inhibit R5 HIV-1 infection through their antagonistic effects on CCR5.
    J Biol Chem, Vol. 276, No. 37. (Sep 2001), pp. 35194-200.
    by K Maeda, K Yoshimura, S Shibayama, H Habashita, H Tada, K Sagawa, T Miyakawa, M Aoki, D Fukushima, H Mitsuya
    posted to antagonist bibtex-nicole ccr5 chemokine gpcr by ndoelker on 2006-10-30 16:53:00 as read along with 1 group LabCompMed
  • International union of pharmacology. XXII. Nomenclature for chemokine receptors
    PHARMACOLOGICAL REVIEWS, Vol. 52, No. 1. (2000), pp. 145-176.
    by PM Murphy, M Baggiolini, IF Charo, CA Hebert, R Horuk, K Matsushima, LH Miller, JJ Oppenheim, CA Power
    posted to bibtex-nicole chemokine gpcr nomenclature by ndoelker on 2006-10-30 16:52:59 as read along with 1 group LabCompMed
  • Molecular anatomy of CCR5 engagement by physiologic and viral chemokines and HIV-1 envelope glycoproteins: differences in primary structural requirements for RANTES, MIP-1 alpha, and vMIP-II Binding.
    J Mol Biol, Vol. 313, No. 5. (Nov 2001), pp. 1181-93.
    by JM Navenot, ZX Wang, JO Trent, JL Murray, QX Hu, L Deleeuw, PS Moore, Y Chang, SC Peiper
    posted to agonist bibtex-nicole binding ccr5 chemokine by ndoelker on 2006-10-30 16:52:59 as read along with 1 group LabCompMed
  • Chemokines, chemokine receptors and small-molecule antagonists: recent developments.
    Trends Pharmacol Sci, Vol. 23, No. 10. (Oct 2002), pp. 459-67.
    by James J Onuffer, Richard Horuk
    posted to agonist antagonist bibtex-nicole chemokine gpcr by ndoelker on 2006-10-30 16:52:59 as read along with 1 group LabCompMed
  • Structure modeling of the chemokine receptor CCR5: implications for ligand binding and selectivity.
    Biophys J, Vol. 83, No. 6. (Dec 2002), pp. 3012-31.
    by Germana M Paterlini
    posted to bibtex-nicole binding ccr5 chemokine gpcr modeling by ndoelker on 2006-10-30 16:52:58 as read along with 1 group LabCompMed
  • SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo.
    Proc Natl Acad Sci U S A, Vol. 98, No. 22. (Oct 2001), pp. 12718-23.
    by JM Strizki, S Xu, NE Wagner, L Wojcik, J Liu, Y Hou, M Endres, A Palani, S Shapiro, JW Clader, WJ Greenlee, JR Tagat, S Mccombie, K Cox, AB Fawzi, CC Chou, Pugliese C Sivo, L Davies, ME Moreno, DD Ho, A Trkola, CA Stoddart, JP Moore, GR Reyes, BM Baroudy
    posted to antagonist bibtex-nicole ccr5 chemokine gpcr by ndoelker on 2006-10-30 16:52:55 as read along with 1 group LabCompMed
  • Identification of a signal transduction switch in the chemokine receptor CXCR1.
    J Biol Chem, Vol. 277, No. 35. (Aug 2002), pp. 31563-6.
    by Katsutoshi Suetomi, Daniel Rojo, Javier Navarro
    posted to bibtex-nicole chemokine cxcr1 gpcr switch by ndoelker on 2006-10-30 16:52:55 as read along with 1 group LabCompMed
  • Piperazine-based CCR5 antagonists as HIV-1 inhibitors. IV. Discovery of 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]- 4-[4-[2-methoxy-1(R)-4-(trifluoromethyl)phenyl]ethyl-3(S)-methyl-1-piperazinyl]- 4-methylpiperidine (Sch-417690/Sch-D), a potent, highly selective, and orally bioavailable CCR5 antagonist.
    J Med Chem, Vol. 47, No. 10. (May 2004), pp. 2405-8.
    by Jayaram R Tagat, Stuart W Mccombie, Dennis Nazareno, Marc A Labroli, Yushi Xiao, Ruo W Steensma, Julie M Strizki, Bahige M Baroudy, Kathleen Cox, Jean Lachowicz, Geoffrey Varty, Robert Watkins
    posted to antagonist bibtex-nicole ccr5 chemokine gpcr by ndoelker on 2006-10-30 16:52:54 as read along with 1 group LabCompMed
  • Molecular docking and 3D QSAR studies on 1-amino-2-phenyl-4-(piperidin-1-yl)-butanes based on the structural modeling of human CCR5 receptor.
    Bioorg Med Chem, Vol. 12, No. 23. (Dec 2004), pp. 6193-208.
    by Yong Xu, Hong Liu, Chunying Niu, Cheng Luo, Xiaomin Luo, Jianhua Shen, Kaixian Chen, Hualiang Jiang
    posted to bibtex-nicole ccr5 chemokine gpcr modeling qsar by ndoelker on 2006-10-30 16:52:53 as read along with 1 group LabCompMed
  • Expression and functional characterization of mutant human CXCR4 in insect cells: role of cysteinyl and negatively charged residues in ligand binding.
    Arch Biochem Biophys, Vol. 373, No. 1. (Jan 2000), pp. 211-7.
    by H Zhou, HH Tai
    posted to bibtex-nicole binding chemokine cxcr4 gpcr by ndoelker on 2006-10-30 16:52:53 as read along with 1 group LabCompMed
  • Molecular modeling and site-directed mutagenesis of CCR5 reveal residues critical for chemokine binding and signal transduction.
    Eur J Immunol, Vol. 30, No. 1. (Jan 2000), pp. 164-73.
    by N Zhou, Z Luo, JW Hall, J Luo, X Han, Z Huang
    posted to bibtex-nicole ccr5 chemokine gpcr modeling mutation by ndoelker on 2006-10-30 16:52:53 as read along with 1 group LabCompMed
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