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ndoelkers crth2 [18 articles]

Artikler nylig sendt til ndoelkers bibliotek klassifisert med nøkkelordet crth2. You can also see everyone's crth2.
  • Novel selective orally active CRTH2 antagonists for allergic inflammation developed from in silico derived hits.
    J Med Chem, Vol. 49, No. 23. (16 November 2006), pp. 6638-6641.
    posted to pharmacophore crth2 antagonist by ndoelker on 2007-01-12 14:48:42 as ***** along with 1 group LabCompMed
  • Indole-3-acetic acid antagonists of the prostaglandin D2 receptor CRTH2.
    J Med Chem, Vol. 48, No. 20. (Oct 2005), pp. 6174-6177.
    by Richard E Armer, Mark R Ashton, Edward A Boyd, Chris J Brennan, Frederick A Brookfield, Lucien Gazi, Shã¢n L Gyles, Philip A Hay, Michael G Hunter, David Middlemiss, Mark Whittaker, Luzheng Xue, Roy Pettipher
    posted to antagonist bibtex-nicole crth2 gpcr by ndoelker on 2006-10-30 16:53:04 as read along with 1 group LabCompMed
  • Identification of determinants of ligand binding affinity and selectivity in the prostaglandin D2 receptor CRTH2.
    J Biol Chem, Vol. 280, No. 37. (Sep 2005), pp. 32442-51.
    by Aaron N Hata, Terry P Lybrand, Richard M Breyer
    posted to bibtex-nicole binding crth2 gpcr by ndoelker on 2006-10-30 16:53:02 as read along with 1 group LabCompMed
  • Structural determinants of arylacetic acid nonsteroidal anti-inflammatory drugs necessary for binding and activation of the prostaglandin D2 receptor CRTH2.
    Mol Pharmacol, Vol. 67, No. 3. (Mar 2005), pp. 640-7.
    by Aaron N Hata, Terry P Lybrand, Lawrence J Marnett, Richard M Breyer
  • Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2.
    J Exp Med, Vol. 193, No. 2. (Jan 2001), pp. 255-261.
  • Emerging roles of DP and CRTH2 in allergic inflammation.
    Trends Mol Med, Vol. 12, No. 4. (Apr 2006), pp. 148-158.
    by Evi Kostenis, Trond Ulven
  • On the mechanism of interaction of potent, surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2.
    Mol Pharmacol (Jan 2006)
    by Jesper M Mathiesen, Arthur Christopoulos, Trond Ulven, Julia Royer, Mercedes Campillo, Akos Heinemann, Leonardo Pardo, Evi Kostenis
  • Identification of indole derivatives exclusively interfering with a G protein-independent signaling pathway of the prostaglandin D2 receptor CRTH2.
    Mol Pharmacol, Vol. 68, No. 2. (Aug 2005), pp. 393-402.
    by Jesper M Mathiesen, Trond Ulven, Lene Martini, Lars O Gerlach, Akos Heinemann, Evi Kostenis
    posted to antagonist bibtex-nicole crth2 gpcr by ndoelker on 2006-10-30 16:53:00 as read along with 1 group LabCompMed
  • Inhibitory effect of the 4-aminotetrahydroquinoline derivatives, selective chemoattractant receptor-homologous molecule expressed on T helper 2 cell antagonists, on eosinophil migration induced by prostaglandin D2.
    J Pharmacol Exp Ther, Vol. 314, No. 1. (Jul 2005), pp. 244-251.
    by Hideki Mimura, Toshihide Ikemura, Osamu Kotera, Masatsugu Sawada, Satoshi Tashiro, Eiichi Fuse, Kimihisa Ueno, Haruhiko Manabe, Etsuo Ohshima, Akira Karasawa, Hiromasa Miyaji
  • The second PGD(2) receptor CRTH2: structure, properties, and functions in leukocytes.
    Prostaglandins Leukot Essent Fatty Acids, Vol. 69, No. 2-3. (2003), pp. 169-77.
    by Kinya Nagata, Hiroyuki Hirai
  • Selective expression of a novel surface molecule by human Th2 cells in vivo.
    J Immunol, Vol. 162, No. 3. (Feb 1999), pp. 1278-1286.
    by K Nagata, K Tanaka, K Ogawa, K Kemmotsu, T Imai, O Yoshie, H Abe, K Tada, M Nakamura, K Sugamura, S Takano
  • Isosteric ramatroban analogs: selective and potent CRTH-2 antagonists.
    Bioorg Med Chem Lett, Vol. 15, No. 6. (Mar 2005), pp. 1749-1753.
    by Michael J Robarge, David C Bom, Nathan L Tumey, Norbert Varga, Elizabeth Gleason, Daniel Silver, Jianping Song, Steven M Murphy, George Ekema, Chris Doucette, Doug Hanniford, Marc Palmer, Gary Pawlowski, Joel Danzig, Margaret Loftus, Karen Hunady, Bruce A Sherf, Robert W Mays, Alain S Krongrad, Kurt R Brunden, John J Harrington, Youssef L Bennani
  • 9alpha,11beta-PGF2 and its stereoisomer PGF2alpha are novel agonists of the chemoattractant receptor, CRTH2.
    FEBS Lett, Vol. 580, No. 2. (Jan 2006), pp. 373-379.
    by Hilary Sandig, David Andrew, Ashley A Barnes, Ian Sabroe, James Pease
  • Molecular pharmacology of the human prostaglandin D2 receptor, CRTH2.
    Br J Pharmacol, Vol. 137, No. 8. (Dec 2002), pp. 1163-1172.
    by Nicole Sawyer, Elizabeth Cauchon, Anne Chateauneuf, Rani PG Cruz, Donald W Nicholson, Kathleen M Metters, Gary P O'Neill, Francois G Gervais
    posted to bibtex-nicole crth2 gpcr pharmacology by ndoelker on 2006-10-30 16:52:56 as read along with 1 group LabCompMed
  • Chemoattractant receptor-homologous molecule expressed on Th2 cells activation in vivo increases blood leukocyte counts and its blockade abrogates 13,14-dihydro-15-keto-prostaglandin D2-induced eosinophilia in rats.
    J Pharmacol Exp Ther, Vol. 307, No. 2. (Nov 2003), pp. 518-525.
    by Michitaka Shichijo, Hiromi Sugimoto, Koichi Nagao, Hisayo Inbe, Jeffrey A Encinas, Keisuke Takeshita, Kevin B Bacon, Florian Gantner
  • An orally bioavailable small molecule antagonist of CRTH2, ramatroban (BAY u3405), inhibits prostaglandin D2-induced eosinophil migration in vitro.
    J Pharmacol Exp Ther, Vol. 305, No. 1. (Apr 2003), pp. 347-352.
    by Hiromi Sugimoto, Michitaka Shichijo, Takashi Iino, Yoshihisa Manabe, Akihiko Watanabe, Makoto Shimazaki, Florian Gantner, Kevin B Bacon
    posted to antagonist bibtex-nicole crth2 gpcr by ndoelker on 2006-10-30 16:52:55 as read along with 1 group LabCompMed
  • CRTH2-specific binding characteristics of [3H]ramatroban and its effects on PGD2-, 15-deoxy-Delta12, 14-PGJ2- and indomethacin-induced agonist responses.
    Eur J Pharmacol, Vol. 524, No. 1-3. (Nov 2005), pp. 30-37.
    by Hiromi Sugimoto, Michitaka Shichijo, Mitsuhiro Okano, Kevin B Bacon
    posted to antagonist bibtex-nicole crth2 gpcr by ndoelker on 2006-10-30 16:52:55 as read along with 1 group LabCompMed
  • Minor structural modifications convert the dual TP/CRTH2 antagonist ramatroban into a highly selective and potent CRTH2 antagonist.
    J Med Chem, Vol. 48, No. 4. (Feb 2005), pp. 897-900.
    by Trond Ulven, Evi Kostenis
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