Construction of multiple-beam optical traps with nanometer-resolution position sensing

@article{citeulike:2224509, abstract = {We describe the design and construction of two different types of multiple-beam optical tweezers, each equipped with nanometer-resolution position detectors. Multiple optical traps can be created either by splitting a laser beam in two parts, based on its polarization, or time-sharing a single beam among several different locations. The advantages and disadvantages of optical tweezers based on either scheme are discussed, along with details of specific implementations. Various ways to detect microscopic movements of an optically trapped object are presented and compared, including designs that are relatively insensitive to absolute location of a trapped particle within the field of view. Two of many possible applications for such instruments are illustrated: the detection of molecular steps by kinesin motor molecules, and determinations of the stiffness of single microtubules}, author = {Visscher, K. and Gross, S. P. and Block, S. M. }, booktitle = {Selected Topics in Quantum Electronics, IEEE Journal of}, citeulike-article-id = {2224509}, doi = {http://dx.doi.org/10.1109/2944.577338}, journal = {Selected Topics in Quantum Electronics, IEEE Journal of}, keywords = {beam, multiple, nanometer, optical, position, sensing, trap, tweezers}, number = {4}, pages = {1066--1076}, posted-at = {2008-01-13 05:39:08}, priority = {2}, title = {Construction of multiple-beam optical traps with nanometer-resolution position sensing}, url = {http://dx.doi.org/10.1109/2944.577338}, volume = {2}, year = {1996} }

TY - JOUR ID - citeulike:2224509 L3 - citeulike-article-id:2224509 TI - Construction of multiple-beam optical traps with nanometer-resolution position sensing T2 - Selected Topics in Quantum Electronics, IEEE Journal of JF - Selected Topics in Quantum Electronics, IEEE Journal of VL - 2 IS - 4 SP - 1066 EP - 1076 N2 - We describe the design and construction of two different types of multiple-beam optical tweezers, each equipped with nanometer-resolution position detectors. Multiple optical traps can be created either by splitting a laser beam in two parts, based on its polarization, or time-sharing a single beam among several different locations. The advantages and disadvantages of optical tweezers based on either scheme are discussed, along with details of specific implementations. Various ways to detect microscopic movements of an optically trapped object are presented and compared, including designs that are relatively insensitive to absolute location of a trapped particle within the field of view. Two of many possible applications for such instruments are illustrated: the detection of molecular steps by kinesin motor molecules, and determinations of the stiffness of single microtubules KW - beam KW - multiple KW - nanometer KW - optical KW - position KW - sensing KW - trap KW - tweezers AU - Visscher, K AU - Gross, SP AU - Block, SM PY - 1996/// UR - http://dx.doi.org/10.1109/2944.577338 ER -