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Computational methods in protein structure prediction.

by: CA Floudas
Biotechnol Bioeng, Vol. 97, No. 2. (1 June 2007), pp. 207-213.


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This review presents the advances in protein structure prediction from the computational methods perspective. The approaches are classified into four major categories: comparative modeling, fold recognition, first principles methods that employ database information, and first principles methods without database information. Important advances along with current limitations and challenges are presented.


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