Accuracy of T1 measurements at high temporal resolution: Feasibility of dynamic measurement of blood T1 after contrast administration

@article{citeulike:841676, abstract = {The purpose of this work was to optimize a technique to measure blood T1 dynamically after contrast agent administration with a high temporal resolution. This technique uses a 90° prepared gradient-echo sequence and has a temporal resolution of one T1 measurement per cardiac cycle. The non-ideal excitation slice profiles on the estimation of T1 were evaluated by theoretical simulations and used to obtain corrected blood T1 values. The technique was validated on phantom and in vivo pig studies, which demonstrated significant improvement on the accuracy of the dynamic T1 measurement method after slice profile correction. This technique may find important applications in studying the dynamic blood T1 after injection of various contrast agents. J. Magn. Reson. Imaging 1999;10:576-581. {\copyright} 1999 Wiley-Liss, Inc.}, address = {Bracco Research USA, Princeton, NJ 08540.; Department of Radiology, Northwestern University, Chicago, Illinois 60611.; Mallinckrodt Institute of Radiology, Washington University Medical School, St. Louis, Missouri 63110.; Bracco S.p.A., Milan, Italy 20134.}, author = {Zheng, Jie and Venkatesan, Ramesh and Haacke, Mark E. and Cavagna, Friedrich M. and Finn, Paul J. and Li, Debiao }, citeulike-article-id = {841676}, doi = {10.1002/(SICI)1522-2586(199910)10:4<576::AID-JMRI11>3.0.CO;2-P}, journal = {Journal of Magnetic Resonance Imaging}, keywords = {artefacts, measurement, mri, t1}, number = {4}, pages = {576--581}, posted-at = {2006-09-13 09:17:51}, priority = {2}, title = {Accuracy of T1 measurements at high temporal resolution: Feasibility of dynamic measurement of blood T1 after contrast administration}, url = {http://dx.doi.org/10.1002/(SICI)1522-2586(199910)10:4\%3C576::AID-JMRI11\%3E3.0.CO;2-P}, volume = {10}, year = {1999} }

TY - JOUR ID - citeulike:841676 L3 - citeulike-article-id:841676 TI - Accuracy of T1 measurements at high temporal resolution: Feasibility of dynamic measurement of blood T1 after contrast administration JF - Journal of Magnetic Resonance Imaging VL - 10 IS - 4 SP - 576 EP - 581 AD - Bracco Research USA, Princeton, NJ 08540.; Department of Radiology, Northwestern University, Chicago, Illinois 60611.; Mallinckrodt Institute of Radiology, Washington University Medical School, St. Louis, Missouri 63110.; Bracco S.p.A., Milan, Italy 20134. N2 - The purpose of this work was to optimize a technique to measure blood T1 dynamically after contrast agent administration with a high temporal resolution. This technique uses a 90° prepared gradient-echo sequence and has a temporal resolution of one T1 measurement per cardiac cycle. The non-ideal excitation slice profiles on the estimation of T1 were evaluated by theoretical simulations and used to obtain corrected blood T1 values. The technique was validated on phantom and in vivo pig studies, which demonstrated significant improvement on the accuracy of the dynamic T1 measurement method after slice profile correction. This technique may find important applications in studying the dynamic blood T1 after injection of various contrast agents. J. Magn. Reson. Imaging 1999;10:576-581. © 1999 Wiley-Liss, Inc. KW - artefacts KW - measurement KW - mri KW - t1 AU - Zheng, Jie AU - Venkatesan, Ramesh AU - Haacke, Mark AU - Cavagna, Friedrich AU - Finn, Paul AU - Li, Debiao PY - 1999/// UR - http://dx.doi.org/10.1002/(SICI)1522-2586(199910)10:4%3C576::AID-JMRI11%3E3.0.CO;2-P ER -