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zhleis library [338 articles]

Nye artikler sendt til zhleis bibliotek.
  • Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1.
    The Biochemical journal, Vol. 405, No. 1. (1 July 2007), pp. 1-9.
    by GL Semenza
    posted to mitochondria hypoxia hif1 by zhlei on 2008-08-19 20:13:38 as **
  • p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling
    Cell, Vol. 134, No. 3. (8 August 2008), pp. 451-460.
    by Andrei V Budanov, Michael Karin
    posted to p53 mtor dna-repair dna-damage by zhlei on 2008-08-08 17:04:55 as ** along with 1 person sarahazl
  • The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control
    Cell, Vol. 134, No. 2. (25 July 2008), pp. 329-340.
    by Yasukazu Nakahata, Milota Kaluzova, Benedetto Grimaldi, Saurabh Sahar, Jun Hirayama, Danica Chen, Leonard P Guarente, Paolo Sassone-Corsi
    posted to sirt1 circadian-clock chromatin-remodeling-modification by zhlei on 2008-08-08 15:10:56 as **
  • SIRT1 regulates circadian clock gene expression through PER2 deacetylation.
    Cell, Vol. 134, No. 2. (25 July 2008), pp. 317-328.
    by G Asher, D Gatfield, M Stratmann, H Reinke, C Dibner, F Kreppel, R Mostoslavsky, FW Alt, U Schibler
    posted to sirt1 deacetylation circadian-clock by zhlei on 2008-08-08 15:10:35 as **
  • A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse.
    Genes & development, Vol. 22, No. 15. (1 August 2008), pp. 2048-2061.
    by G Schotta, R Sengupta, S Kubicek, S Malin, M Kauer, E Callén, A Celeste, M Pagani, S Opravil, IA De La Rosa-Velazquez, A Espejo, MT Bedford, A Nussenzweig, M Busslinger, T Jenuwein
    posted to monomethylation methylation h4k20 dna-repair dna-damage by zhlei on 2008-08-07 23:24:43 as **
  • A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation.
    Genes & development, Vol. 22, No. 15. (1 August 2008), pp. 2062-2074.
    by YY Lin, Y Qi, JY Lu, X Pan, DS Yuan, Y Zhao, JS Bader, JD Boeke
    posted to yeast histone deacetylation acetylation by zhlei on 2008-08-07 23:22:45 as **
  • Substrates and regulation mechanisms for the human mitochondrial Sirtuins Sirt3 and Sirt5
    Journal of Molecular Biology, Vol. In Press, Accepted Manuscript
    by Christine Schlicker, Melanie Gertz, Panagiotis Papatheodorou, Barbara Kachholz, Christian F Becker, Clemens Steegborn
    posted to sirtuin sirt5 sirt3 mitochondria by zhlei on 2008-08-07 14:28:02 as **
  • Down-regulation of a SILENT INFORMATION REGULATOR2-related histone deacetylase gene, OsSRT1, induces DNA fragmentation and cell death in rice.
    Plant physiology, Vol. 144, No. 3. (July 2007), pp. 1508-1519.
    by L Huang, Q Sun, F Qin, C Li, Y Zhao, DX Zhou
    posted to sirt2 plant methylation h3k9 dna-damage dimethylation by zhlei on 2008-08-06 18:05:50 as **
  • HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption.
    Cell Metab, Vol. 3, No. 3. (March 2006), pp. 187-197.
    by I Papandreou, RA Cairns, L Fontana, AL Lim, NC Denko
    posted to mitochondria metabolism lactate hypoxia hif1 glucose by zhlei on 2008-08-04 22:47:30 as ** along with 1 person robacairns
  • Coming up for air: HIF-1 and mitochondrial oxygen consumption
    Cell Metabolism, Vol. 3, No. 3. (March 2006), pp. 150-151.
    by Celeste M Simon
    posted to metabolism lactate hypoxia hif1 by zhlei on 2008-08-04 22:32:52 as **
  • HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia.
    Cell metabolism, Vol. 3, No. 3. (March 2006), pp. 177-185.
    by JW Kim, I Tchernyshyov, GL Semenza, CV Dang
    posted to pdk metabolism lactate hypoxia hif1 by zhlei on 2008-08-04 22:30:15 as **
  • The human CENP-A centromeric nucleosome-associated complex
    Nature Cell Biology, Vol. 8, No. 5. (16 April 2006), pp. 458-469.
    by Daniel R Foltz, Lars ET Jansen, Ben E Black, Aaron O Bailey, John R Yates, Don W Cleveland
    posted to nucleosome ip chromatin by zhlei on 2008-07-30 17:29:20 as ** along with 1 person stonest
  • Early Events in the Mammalian Response to DNA Double-Strand Breaks
    Mutagenesis (21 July 2008), gen039.
    by Lucy C Riches, Anthony M Lynch, Nigel J Gooderham
    posted to review dna-damage by zhlei on 2008-07-24 02:35:05 as **
  • Tumor cell metabolism: cancer's Achilles' heel.
    Cancer cell, Vol. 13, No. 6. (June 2008), pp. 472-482.
    by G Kroemer, J Pouyssegur
    posted to metabolism glycolysis cancer by zhlei on 2008-07-14 23:17:08 as **
  • How to measure insulin sensitivity.
    J Hypertens, Vol. 16, No. 7. (July 1998), pp. 895-906.
    by E Ferrannini, A Mari
    posted to insulin-sensitivity insulin by zhlei on 2008-07-14 19:55:08 as ** along with 1 person FW_Gibb
  • Overfeeding Rapidly Induces Leptin and Insulin Resistance
    Diabetes, Vol. 50, No. 12. (1 December 2001), pp. 2786-2791.
    by Jiali Wang, Silvana Obici, Kimyata Morgan, Nir Barzilai, Zhaohui Feng, Luciano Rossetti
    posted to insulin-sensitivity insulin by zhlei on 2008-07-14 19:54:18 as **
  • Glucose metabolism and cancer
    Current Opinion in Cell Biology, Vol. 18, No. 6. (December 2006), pp. 598-608.
    by Reuben J Shaw
    posted to review metabolism glucose cancer by zhlei on 2008-07-14 17:44:53 as **
  • Pre-genomic, genomic and post-genomic study of microbial communities involved in bioenergy.
    Nature reviews. Microbiology (7 July 2008)
    by Bruce E E Rittmann, Rosa Krajmalnik-Brown, Rolf U U Halden
    posted to biofuel by zhlei on 2008-07-11 16:54:47 as **
  • DNA repair, insulin signaling and sirtuins: at the crossroads between cancer and aging.
    Frontiers in bioscience : a journal and virtual library, Vol. 13 (2008), pp. 6966-6990.
    by R Mostoslavsky
    posted to sirtuin review insulin ifg1 dna-damage cancer aging by zhlei on 2008-07-08 20:32:15 as read
  • Minireview: Role of the Growth Hormone/Insulin-Like Growth Factor System in Mammalian Aging
    Endocrinology, Vol. 146, No. 9. (1 September 2005), pp. 3718-3723.
    by Andrzej Bartke
    posted to review insulin igf1 aging by zhlei on 2008-07-08 19:44:20 as ** along with 1 person meghan81
  • Human cell senescence as a DNA damage response
    Mechanisms of Ageing and Development, Vol. 126, No. 1. (January 2005), pp. 111-117.
    by Von T Zglinicki, G Saretzki, J Ladhoff, Fagagna, SP Jackson
    posted to telomere senescence aging by zhlei on 2008-07-07 17:58:45 as **
  • DNA damage signalling guards against activated oncogenes and tumour progression.
    Oncogene, Vol. 26, No. 56. (10 December 2007), pp. 7773-7779.
    by J Bartek, J Bartkova, J Lukas
    posted to review dna-damage cancer by zhlei on 2008-07-07 17:56:00 as ** along with 1 person catcremona
  • The role of the DNA damage response pathways in brain development and microcephaly: Insight from human disorders
    DNA Repair, Vol. In Press, Corrected Proof
    by Mark O'Driscoll, Penny A Jeggo
    posted to review dna-damage by zhlei on 2008-07-07 17:30:30 as ** along with 1 person TOchi
  • The Ongoing Saga of Sirtuins and Aging
    Cell Metabolism, Vol. 8, No. 1. (2 July 2008), pp. 4-5.
    by Matt Kaeberlein
    posted to sirt1 review aging by zhlei on 2008-07-02 21:42:02 as **
  • SirT1 Inhibition Reduces IGF-I/IRS-2/Ras/ERK1/2 Signaling and Protects Neurons
    Cell Metabolism, Vol. 8, No. 1. (2 July 2008), pp. 38-48.
    by Ying Li, Wei Xu, Michael W Mcburney, Valter D Longo
    posted to sirtuin sirt1 igf1 by zhlei on 2008-07-02 21:39:51 as **
  • Epigenetic control of rDNA loci in response to intracellular energy status.
    Cell, Vol. 133, No. 4. (16 May 2008), pp. 627-639.
    by A Murayama, K Ohmori, A Fujimura, H Minami, K Yasuzawa-Tanaka, T Kuroda, S Oie, H Daitoku, M Okuwaki, K Nagata, A Fukamizu, K Kimura, T Shimizu, J Yanagisawa
    posted to sirtuin sir1 rdna by zhlei on 2008-07-02 21:02:28 as ** along with 1 person slevy03
  • A Metabolic Throttle Regulates the Epigenetic State of rDNA
    Cell, Vol. 133, No. 4. (16 May 2008), pp. 577-580.
    by Ingrid Grummt, Andreas G Ladurner
    posted to sirtuin sirt1 review rdna by zhlei on 2008-07-02 20:59:30 as ** along with 1 person slevy03
  • The FACT Spt16 "peptidase" domain is a histone H3-H4 binding module
    Proceedings of the National Academy of Sciences (25 June 2008), 0712293105.
    by Tobias Stuwe, Michael Hothorn, Erwan Lejeune, Vladimir Rybin, Miriam Bortfeld, Klaus Scheffzek, Andreas G Ladurner
    posted to spt16 fact by zhlei on 2008-07-01 02:13:08 as **
  • Sirtuins: Novel targets for metabolic disease in drug development
    Biochemical and Biophysical Research Communications, Vol. In Press, Corrected Proof
    by Wei-Jian Jiang
    posted to sirtuin review by zhlei on 2008-06-30 20:51:10 as **
  • WHY DO CANCERS HAVE HIGH AEROBIC GLYCOLYSIS?
    Nat Rev Cancer, Vol. 4, No. 11. (November 2004), pp. 891-899.
    by Robert A Gatenby, Robert J Gillies
    posted to glycolysis cancer by zhlei on 2008-06-20 20:18:11 as ** along with 1 person laurabailey
  • An elaborate pathway required for Ras-mediated epigenetic silencing
    Nature, Vol. 449, No. 7165., pp. 1073-1077.
    by Claude Gazin, Narendra Wajapeyee, Stephane Gobeil, Ching-Man Virbasius, Michael R Green
    posted to sirt6 chip by zhlei on 2008-06-20 15:55:22 as ** along with 2 people jackjackjjj SciNika
  • An embryoprotective role for glucose-6-phosphate dehydrogenase in developmental oxidative stress and chemical teratogenesis.
    The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 14, No. 1. (January 2000), pp. 111-127.
    by CJ Nicol, J Zielenski, LC Tsui, PG Wells
    posted to g6pd by zhlei on 2008-06-05 22:26:26 as **
  • SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase.
    The Journal of biological chemistry (14 May 2008)
    by Xiuyun Hou, Shanqin Xu, Karlene A A Maitland-Toolan, Kaori Sato, Bingbing Jiang, Yasuo Ido, Fan Lan, Kenneth Walsh, Michel Wierzbicki, Tony J J Verbeuren, Richard A A Cohen
    posted to sirt1 metabolism by zhlei on 2008-05-18 22:10:53 as ** along with 1 person jyuh
  • SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
    Nature (12 March 2008)
    by Eriko Michishita, Ronald A Mccord, Elisabeth Berber, Mitomu Kioi, Hesed Padilla-Nash, Mara Damian, Peggie Cheung, Rika Kusumoto, Tiara LA Kawahara, Carl J Barrett, Howard Y Chang, Vilhelm A Bohr, Thomas Ried, Or Gozani, Katrin F Chua
    posted to telomere sirtuin sirt6 histone h3k9 acetylation by zhlei on 2008-05-01 23:19:25 as ** along with 1 person biomcgary
  • AKT/PKB signaling: navigating downstream.
    Cell, Vol. 129, No. 7. (29 June 2007), pp. 1261-1274.
    by BD Manning, LC Cantley
    posted to review akt by zhlei on 2008-04-29 18:21:18 as ** along with 3 people voldog jyuh lisa1
  • Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks.
    J Cell Biol, Vol. 173, No. 2. (24 April 2006), pp. 195-206.
    by S Bekker-Jensen, C Lukas, R Kitagawa, F Melander, MB Kastan, J Bartek, J Lukas
    posted to dna-pk dna-damage atr atm by zhlei on 2008-04-29 17:59:25 as ** along with 1 person DNAReplication
  • Sir2 Deacetylates Histone H3 Lysine 56 to Regulate Telomeric Heterochromatin Structure in Yeast
    Molecular Cell, Vol. 27, No. 6. (21 September 2007), pp. 890-900.
    by Feng Xu, Qiongyi Zhang, Kangling Zhang, Wei Xie, Michael Grunstein
    posted to yeast telomere sir2 heterochromatin by zhlei on 2008-04-28 23:06:15 as ** along with 1 person onufriev
  • PKB[alpha]/Akt1 Acts Downstream of DNA-PK in the DNA Double-Strand Break Response and Promotes Survival
    Molecular Cell, Vol. 30, No. 2. (25 April 2008), pp. 203-213.
    by Lana Bozulic, Banu Surucu, Debby Hynx, Brian A Hemmings
    posted to dna-damage akt by zhlei on 2008-04-28 23:04:28 as **
  • The DNA damage response pathways: at the crossroad of protein modifications.
    Cell Res, Vol. 18, No. 1. (January 2008), pp. 8-16.
    by MS Huen, J Chen
    posted to dna-damage by zhlei on 2008-04-25 19:23:58 as ** along with 1 person jyuh
  • Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice
    Circ Res, Vol. 102, No. 6. (28 March 2008), pp. 703-710.
    by Olesya Vakhrusheva, Christian Smolka, Praveen Gajawada, Sawa Kostin, Thomas Boettger, Thomas Kubin, Thomas Braun, Eva Bober
    posted to sirt7 by zhlei on 2008-04-25 16:06:51 as **
  • Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription
    Genes Dev., Vol. 20, No. 9. (1 May 2006), pp. 1075-1080.
    by Ethan Ford, Renate Voit, Gregory Liszt, Cornelia Magin, Ingrid Grummt, Leonard Guarente
    posted to sirtuin sirt7 by zhlei on 2008-04-25 00:37:55 as **
  • SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes.
    The Journal of biological chemistry, Vol. 280, No. 14. (8 April 2005), pp. 13560-13567.
    by T Shi, F Wang, E Stieren, Q Tong
    posted to sirt3 by zhlei on 2008-04-25 00:01:19 as **
  • Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress
    Cell Metabolism, Vol. 2, No. 1. (July 2005), pp. 67-76.
    by Katrin F Chua, Raul Mostoslavsky, David B Lombard, Wendy W Pang, Shin'ichi Saito, Sonia Franco, Dhruv Kaushal, Hwei-Ling Cheng, Miriam R Fischer, Nicole Stokes, Michael M Murphy, Ettore Appella, Frederick W Alt
    posted to sirt1 senescence by zhlei on 2008-04-24 19:32:48 as **
  • Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras–MAPK signaling in human cancer cells
    Oncogene, Vol. aop, No. current.
    by H Ota, E Tokunaga, K Chang, M Hikasa, K Iijima, M Eto, K Kozaki, M Akishita, Y Ouchi, M Kaneki,
    posted to sirt1 by zhlei on 2008-04-24 18:33:40 as **
  • E2F1-Regulated MicroRNAs Impair TGF[beta]-Dependent Cell-Cycle Arrest and Apoptosis in Gastric Cancer
    Cancer Cell, Vol. 13, No. 3. (11 March 2008), pp. 272-286.
    by Fabio Petrocca, Rosa Visone, Mariadele R Onelli, Manisha H Shah, Milena S Nicoloso, Ivana de Martino, Dimitrios Iliopoulos, Emanuela Pilozzi, Chang-Gong Liu, Massimo Negrini, Luigi Cavazzini, Stefano Volinia, Hansjuerg Alder, Luigi P Ruco, Gustavo Baldassarre, Carlo M Croce, Andrea Vecchione
    posted to mirna by zhlei on 2008-04-21 15:13:41 as ** along with 1 person maralena
  • The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth.
    PLoS ONE, Vol. 3, No. 4. (2008)
    by R Firestein, G Blander, S Michan, P Oberdoerffer, S Ogino, J Campbell, A Bhimavarapu, S Luikenhuis, R de Cabo, C Fuchs, WC Hahn, LP Guarente, DA Sinclair
    posted to cancer sirt1 by zhlei on 2008-04-18 14:47:25 as ** along with 1 person jyuh
  • The deacetylase HDAC6 is a novel critical component of stress granules involved in the stress response
    Genes Dev., Vol. 21, No. 24. (15 December 2007), pp. 3381-3394.
    by Sohee Kwon, Yu Zhang, Patrick Matthias
    posted to dna-damage g3bp by zhlei on 2008-04-10 19:14:12 as ** along with 1 person kbjcflyer
  • Sirtuins in aging and age-related disease.
    Cell, Vol. 126, No. 2. (28 July 2006), pp. 257-268.
    by VD Longo, BK Kennedy
    posted to aging cancer sirt1 sirtuin by zhlei on 2008-04-08 22:24:32 as **
  • The p66shc adaptor protein controls oxidative stress response and life span in mammals.
    Nature, Vol. 402, No. 6759. (18 November 1999), pp. 309-313.
    by E Migliaccio, M Giorgio, S Mele, G Pelicci, P Reboldi, PP Pandolfi, L Lanfrancone, PG Pelicci
    posted to aging lifespan mitochondria p66shc ros by zhlei on 2008-04-04 21:15:48 as **
  • Sir2 and calorie restriction in yeast: A skeptical perspective
    Ageing Research Reviews, Vol. 6, No. 2. (August 2007), pp. 128-140.
    by Matt Kaeberlein, Powers
    posted to yeast sir2 cr calorie-restriction by zhlei on 2008-04-03 14:52:49 as **
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