Molecular and Genomic Data Identify the Closest Living Relative of Primates

@article{citeulike:1857456, abstract = {A full understanding of primate morphological and genomic evolution requires the identification of their closest living relative. In order to resolve the ancestral relationships among primates and their closest relatives, we searched multispecies genome alignments for phylogenetically informative rare genomic changes within the superordinal group Euarchonta, which includes the orders Primates, Dermoptera (colugos), and Scandentia (treeshrews). We also constructed phylogenetic trees from 14 kilobases of nuclear genes for representatives from most major primate lineages, both extant colugos, and multiple treeshrews, including the pentail treeshrew, Ptilocercus lowii, the only living member of the family Ptilocercidae. A relaxed molecular clock analysis including Ptilocercus suggests that treeshrews arose approximately 63 million years ago. Our data show that colugos are the closest living relatives of primates and indicate that their divergence occurred in the Cretaceous. 10.1126/science.1147555}, author = {Janecka, Jan E. and Miller, Webb and Pringle, Thomas H. and Wiens, Frank and Zitzmann, Annette and Helgen, Kristofer M. and Springer, Mark S. and Murphy, William J. }, citeulike-article-id = {1857456}, doi = {10.1126/science.1147555}, journal = {Science}, keywords = {evolution, genome}, month = {November}, number = {5851}, pages = {792--794}, posted-at = {2007-11-05 14:33:23}, priority = {2}, title = {Molecular and Genomic Data Identify the Closest Living Relative of Primates}, url = {http://dx.doi.org/10.1126/science.1147555}, volume = {318}, year = {2007} }

TY - JOUR ID - citeulike:1857456 L3 - citeulike-article-id:1857456 TI - Molecular and Genomic Data Identify the Closest Living Relative of Primates JF - Science VL - 318 IS - 5851 SP - 792 EP - 794 N2 - A full understanding of primate morphological and genomic evolution requires the identification of their closest living relative. In order to resolve the ancestral relationships among primates and their closest relatives, we searched multispecies genome alignments for phylogenetically informative rare genomic changes within the superordinal group Euarchonta, which includes the orders Primates, Dermoptera (colugos), and Scandentia (treeshrews). We also constructed phylogenetic trees from 14 kilobases of nuclear genes for representatives from most major primate lineages, both extant colugos, and multiple treeshrews, including the pentail treeshrew, Ptilocercus lowii, the only living member of the family Ptilocercidae. A relaxed molecular clock analysis including Ptilocercus suggests that treeshrews arose approximately 63 million years ago. Our data show that colugos are the closest living relatives of primates and indicate that their divergence occurred in the Cretaceous. 10.1126/science.1147555 KW - evolution KW - genome AU - Janecka, Jan AU - Miller, Webb AU - Pringle, Thomas AU - Wiens, Frank AU - Zitzmann, Annette AU - Helgen, Kristofer AU - Springer, Mark AU - Murphy, William PY - 2007/11/02/ UR - http://dx.doi.org/10.1126/science.1147555 ER -