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MHC, TSP, and the Origin of Species: From Immunogenetics to Evolutionary Genetics

Annual Review of Genetics, Vol. 41, No. 1., 281.

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http://arjournals.annualreviews.org/doi/f…

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accuracy algorithm alignment annotation antibody archaea architecture assembly bacterial bayesian bifc binding biofuel bioinformatics bootstrap bret bsi cancer cellcycle chaperone chromatin chromosome clade clustering co-evolution co-extinction coil collaboration comparativegenomics compensatory complex computational confidence contact counter cpg-island culture database degradation deletion design differentiation disease divergence diversity dna docking domain duplication dynamics ecoli ecology element em emulation endogenous epigenetics epistasis epitope eukaryota evolution experiment expression fitness fluorescent folding fret function gene geneexpression genefamily geneontology generegulation genetic genetics genome genome-wide hgt hierarchical histone hiv hla hmm homology homologymodeling hostspecialization hub human immunity immunohistochemistry influenza information-theory insilico integration interaction interface invitro invivo lgt likelihood linker localization magnetic mammal massspectrometry massspectroscopy mathematic membrane metabolism methylation mhc mi microarray microrna modeling module molecularrecognition morphological motif mp mrp mutation nanopore nanoscale nature ncrna neoselection network neural nmr noise nuclear oligonucleotide oral ortholog pathobiology pathway pca peptide phenotype phosphorylation phylogeny phylogeography positiveepistasis prediction presentation profile prokaryote promoter protection protein proteome protocol purification qtl regulation regulatory reliability research residue reverse-engineering review ribosome ribozyme rna rnasep rule sampling science secondary selection sequence similarity simulation singlecell singlemolecule site social speciation specy stability statistical structure substitution subunit surface svm synthetic system systematic tag tap target technique text-mining theory threading tissue tlr transcription translation transmembrane trna vesicle viability video virus visualization web y2h yeast ysd